MSc in Genetic Manipulation & Molecular Biosciences. I build bioinformatics pipelines, GPU‑accelerated simulations, and immersive hardware like the LumiFur visor system.
Brighton‑based bioinformatician and 3D‑printing entrepreneur.
I design robust, reproducible analysis tooling for genomics (RNA‑seq batch correction, QC dashboards, containerised workflows) and craft high‑performance visual interfaces.
On the hardware side, I prototype embedded systems for wearables and interactive displays, shipping turnkey kits and custom parts via my company, Richies 3D Ltd.
My MSc dissertation, Evaluating Bulk RNASeq Batch Correction Processes, benchmarks ComBat, Limma, RUVSeq, SVA, and neural approaches to deliver best‑practice guidance for harmonising clinical cohorts.
Earlier, my BSc dissertation carried out molecular dynamics on Sertraline binding to the zebrafish serotonin transporter, coupling binding free energy and RMSD metrics to highlight translational toxicology considerations.
Selected work spanning software, research, and hardware.
Comparative analysis of empirical Bayes and surrogate variable approaches across multi‑cohort bulk RNA‑seq datasets with integration metrics (kBET, iLISI, silhouette).
In silico molecular dynamics of Sertraline complexes with Danio rerio serotonin transporter (drSERTaa) using binding free energy and RMSD analysis to probe bioavailability risks.
BLE‑controlled protogen visor system (ESP‑IDF + Hub75 DMA) with iOS/watchOS companion app in SwiftUI.
Unsupervised neural network for bulk RNA‑seq batch correction with evaluation metrics (kBET, iLISI, silhouette).
GPU‑accelerated orbital visualizer producing probability density maps and isosurfaces.
FDM & resin printing for anatomical models and fursuit components. Etsy storefront and custom commissions.
Recent posts and threads from my professional feed.
Thread unpacking how kBET, iLISI, and silhouette scores guided my benchmarking of bulk RNA-seq batch correction models across clinical cohorts.
LumiFur Controller firmware tipped past 3,200 lines of tightly orchestrated C++ across ESP-IDF, FreeRTOS, Arduino, and a custom animation stack.
Electron Orbital Simulator, a WebGPU & WebGPU based visualiser for hydrogen-like electron orbitals. 🔬
shock diamonds - thruster effect created with EmberGen, by Steph Ritchie
Education and highlights.
Open to bioinformatics roles, research collaborations, and custom builds.
Email me for opportunities, commissions, or speaking: stef1949.sr@outlook.com
Exploring PhD/industry bioinformatics roles in the UK/EU.
Iterating on HarmonizeNN & LumiFur v2 hardware.
Commission slots: open.